IgD myeloma.

igd myeloma

igd myeloma is very rate. it differs from multiple myeloma of other classes in several aspects and its laboratory diagnosis may be difficult, as total plasma protein concentration is often normal, and a paraprotein peak may not be easily demonstrable by the conventional electrophoretic techniques. we report here two cases of igd myeloma investigated in this laboratory. immunochemical, biochemic...

IgD myeloma and acute myelomonocytic leukemia.

IgD Myeloma or Heavy - Chain Disease ?

CLINICAL CHEMISTRY, Vol. 26, No. 2, 1980 353 F.R.G.) of r = 0.95, as well as between the former method and a radioimmunoassay method (CIS-SORIN, Biomedica, 13040 Saluggia, Italy) of r = 0.92. The lackof correlation between serum ferritin and serum iron on one hand and the inverse relationship between serum ferritin and iron-binding capacity on the other, reported by Fortier et al. (1) and by Li...

IgD-kappa myeloma: an unusual case.

A rare case of biclonal IgD-kappa and IgG-kappa myeloma is described. The patient initially presented with anemia, renal insufficiency, and proteinuria. The IgD-kappa, initially, was overlooked as a light chain; however, it decreased in serum concentration after treatment by approximately 90%, in contrast to the IgG-kappa that decreased in serum by approximately 40 % over a 9-yr period. Clinica...

Aggressive FLC Escape in a Patient with IgD Myeloma

Background. Some patients who are stable or in remission from a myeloma secreting intact monoclonal immunoglobulin (+/- associated free light-chains (FLCs)) relapse with production of FLC. This FLC escape is one of the illustrations of the intraclonal heterogeneity of multiple myeloma. Results. We report FLC escape in a patient with IgD myeloma characterized by a severe outcome. We discuss para...